Acid, California sunshine… Much stigma and demonization has been done around this beautiful chemical. Discovered by Albert Hoffman in 1938, this natural chemical, found on the Rye berry, and since recreated in his lab, became one of the most studied chemicals in medical health history.
Due to this microscopic substance, the discovery of serotonin was made widespread, as well as discovering that certain chemicals, like LSD were effective in minuscule amounts, measured in micrograms. Previously, before LSD research, the smallest dosage was done in milligrams, much higher amounts. LSD truly is a wonder-drug that has changed the face of modern medicine.
LSD was made illegal in the late 1960’s, due, many believe to the uprising the US government was facing to their war efforts and conscripting the youth of the day for the Vietnam war. Some believe it was also fuelled by the fear the establishment was having to how this “drug” was opening people minds to new ways of thinking.
Much research was done prior to this change in status, and hundreds if not thousands of cases were reported for how this was helping people deal with mental illness, psychedelic assisted therapy, problem-solving therapy for engineers, architects, etc, and in spiritual awareness therapy.
LSD microdosing provides a sub-perceptual way to interact with this molecule, and the chemistry that takes place in the neural pathways provide a subtle yet powerful way to increase your ability to think more clearly, bring about flow states, and allow your mind to get a natural supercharge in day to day living.
As with Psilocybin, classic psychedelics share a similar structure to serotonin, and work along a similar pathway.
Many antidepressants (called Selective Serotonin Reuptake Inhibitors, or SSRIs) try to make serotonin more plentiful in the brain to make you feel better.
Psychedelics work more directly, by mimicking serotonin. This means that one of their main effects is to stimulate a serotonin receptor, located in the prefrontal cortex, called “5-HT2A.”
The stimulation of the 5-HT2A receptor leads to two very important results:
- The production of “Brain Derived Neurotrophic Factor” (BDNF). BDNF is “like Miracle-Gro for your brain. It stimulates growth, connections, and activity.”
- The increased transmission of “Glutamate.” Glutamate is the neurotransmitter most responsible for brain functions like cognition, learning, and memory.
Glutamate and BDNF work together in ways we’re still understanding, but it’s become clear that having more of each leads to many of the benefits we all seek from microdosing.]
Another thing psychedelics do is to cause parts of the brain that might not usually communicate with one another… to communicate with one another!
Psychedelics allow these unique connections to be formed by dampening the activity of an often over-used part of our brain called the “Default Mode Network” (DMN).
The Default Mode Network is an area of the brain used for an array of different mental activities, including day-dreaming, self-reflection, and thinking about the past or the future. Some studies suggest that depression is linked to an overactive DMN. It’s possible that a highly active DMN causes us to ruminate, over-analyze ourselves, and step out of the present moment to constantly question the past and the future.
This helps explain why these substances could be used to combat depression and anxiety, and also lead to insights and creative perspectives that otherwise remain inaccessible to us.
All of us, at some point in our lives, have experienced a flow state. The surfer effortlessly riding a big wave, the therapist perfectly in-sync with her client, the salesman working the room in an out of body experience… all are examples of people performing at their best while in flow.
Simply put, flow is truly one of the great experiences of being human.
We have no specific, non-anecdotal evidence to suggest that microdoses of psychedelics can induce flow states – but we know that moderate doses can change the function of the brain in a way very similar to that seen in flow states.
Studies show that moderate doses of psychedelics cause brain waves to shift more towards alpha oscillations, which is also seen in the transition to a flow state.
Psychedelics imitate the neurotransmitter serotonin when they enter the brain – and we know that serotonin is found in higher levels in flow states. Similarly, psychedelics increase the levels of dopamine in the brain, another neurotransmitter which is found in higher levels in flow states.
Perhaps most importantly, psychedelics’ ability to dampen down the DMN can allow our brains to make unique connections between areas that don’t usually communicate. This is crucial for allowing flow states to occur.
Since we know that moderate doses of psychedelics can induce similar effects to a flow state in the brain, it seems likely that a regular microdosing regimen will start to shift our awareness in the direction of flow.
HOW DO I MICRODOSE LSD
The option we provide here in the store is a spray bottle that has distilled water with LSD dissolved in the water, allowing for very precise dosing. The spray bottle allows you to measure in 2 microgram increments per spray the amount you are taking. Typically, the dosage is about 5 sprays, or 10 micrograms for a microdose. Some find that too high and others require double that amount, based somewhat on body weight and people individual reception to the medicine, but we are finding 10 micrograms to be an average effective microdose.